David A. Sinclair is a tenured Professor of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for Biology of Aging Research.
Heās a pioneer in aging research, renowned for discovering how molecules like NADāŗ and enzymes called sirtuins influence lifespanāand for identifying small-molecule āsirtuin activatorsā that mimic benefits of caloric restriction. His lab also leads cutting-edge work on epigenetic regulation of aging and cellular reprogramming to reverse age-related changes.
Sinclair has authored 200+ peer-reviewed papers, is co-inventor on over 50 patents, and co-founded several biotech firmsābridging academic insight with translational medicine. He also wrote the bestseller Lifespan: Why We Ageāand Why We Donāt Have To, helping bring scientific discussions of longevity and healthy aging to a global audience.